https://doi.org/10.36719/2663-4619/110/71-74
Vafa Nasirova
Azerbaijan Medical University
Doctor of Philosophy in Medicine
https://orcid.org/ 0000-0002-9848-3455
Sevinj Ahmadova
Azerbaijan Medical University
Doctor of Philosophy in Medicine
https://orcid.org/ 0000-0002-1700-7802
Use of Polymerase Chain Reaction in the Diagnosis of Eye Mycoses
Abstract
The article provides brief information on the use of polymerase chain reaction in the diagnostics of ocular mycoses and shares the successes and experience gained in studying this problem in recent years. Polymerase chain reaction (PCR) is currently considered a sensitive and specific test for the diagnosis of fungal etiological lesions of the organ of vision. Currently, direct microscopic examination and cultivation of corneal material are the "gold standard" for diagnosis. However, rapid, sensitive, but specific tests are required to detect small numbers of or non-viable fungi. PCR has many potential advantages when used as a diagnostic tool for mycotic keratitis. The detected clinical features of mycotic lesions of the organ of vision are of great practical importance for ophthalmologists in the timely clinical diagnosis of a specific process developing in the eye. The developed algorithm of complex therapy of ophthalmomycosis, which takes into account the localization of the process and the types of fungi - the causative agents of mycosis of the eyes, will allow to reduce the number of relapses of the disease, shorten the treatment period of patients with mycosis of the eyes, and reduce the number of unsatisfactory outcomes.
Keywords: ocular mycoses, polymerase chain reaction, diagnostics, etiological structure, fungal keratitis