DOI: 10.36719/2707-1146/05/17-20
Mirza Mikayil Aliyev
Azerbaijan State Agrarian University
mirza.aliyev43@mail.ru
Ulduz Yunis Safarova
Azerbaijan State Agrarian University
ulduzsafar@gmail.com
Shafiqa Jahangir Jafarova
Azerbaijan State Agrarian University
shafiqajafarova@gmail.com

CHARACTERISTICS AND THERAPEUTIC EFFECTS OF THE NOVEL
FREE RADICAL SCAVENGER – EDARAVONE
Summary 
Edaravone is the first free radical scavenger which approved clinically and has an ability to decrease the level of free radicals in cells. Edaravone is a strong antioxidant, which can protect different cells (e.g. endothelial cells) against damage by ROS by inhibiting the lipoxygenase metabolism of arachidonic acid, by trapping hydroxyl radicals, by increasing prostacyclin production, by inhibiting alloxan-induced lipid peroxidation, etc. Because of that, Edaravone is used in treatment of diseases which are associated with oxidative stress.

Key words: edaravone, free radical, antioxidant, neuroprotective agent, oxidative stress

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